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KMID : 1142520220100030101
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Korean Journal of Clinical Dental Hygiene
2022 Volume.10 No. 3 p.101 ~ p.108
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Evaluation of the Antibacterial Effect of Mixed Lidocagle and Propolis
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Heo Su-Hyeon
Bae Sung-Suk
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Abstract
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Objectives: This study attempted to verify the antibacterial effect of a lidocagle solution mixed with propolis, at different concentrations, against S. mutans, S. salivarius, and S. mitis.
Methods: The disk diffusion method, bacterial activity test, and colony formation evaluation assay were performed to evaluate the antibacterial activity of the solutions. Collected data were analyzed by one-way ANOVA and Tukey's post hoc analyses in SPSS 21.0 ver. (SPSS Inc., Chicago, IL, USA); statistical significance was set at 0.05.
Results: In the disc diffusion assay, the diameter of the inhibition zone decreased in media containing Lidocagle and propolis at a high concentration (30 vol%). In contrast, in the bacterial activity evaluation test, bacterial activity increased in media containing propolis an high Lidocagle solution concentrations (except for that at 10% vol). In the colony formation evaluation test, the highest number of colonies was formed in media with propolis and a low concentration of the Lidocagle solution (p<0.05).
Conclusions: The results suggest that the antibacterial effect depends on the Lidocagle:propoli ratio in the medium. Results also showed that 10%, 20%, and 30% Lidocagle solution volume mixes had partial antibacterial effect against S. mutans, S. salivarius, and S. mitis.
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KEYWORD
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Antibacterial activity, Lidocaine, Oral bacteria, Propolis
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